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Article

TDP-1 and FUST-1 co-inhibit exon inclusion and control fertility together with transcriptional regulation.

Nucleic acids research - 13 Oct 2023

Taylor Morgan, Marx Olivia, Norris Adam

Abstract excerpt

Gene expression is a multistep process and crosstalk among regulatory layers plays an important role in coordinating gene expression. To identify functionally relevant gene expression coordination, we performed a systematic reverse-genetic interaction screen in C. elegans, combining RNA binding protein (RBP) and transcription factor (TF) mutants to generate over 100 RBP;TF double mutants. We identified many...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37587694
DOI: 10.1093/nar/gkad665
PMCID: PMC10570059

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TF

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