Article

Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response

2023-06-15

Abstract excerpt

<h4>Background</h4> Statins lower circulating low-density lipoprotein cholesterol (LDLC) levels and reduce cardiovascular disease risk. Though highly efficacious in general, there is considerable inter-individual variation in statin efficacy that remains largely unexplained. <h4>Methods</h4> To identify novel genes that may modulate statin-induced LDLC lowering, we used RNA-sequencing data from 426 control- and...

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Literature Corpus work: 4934ffd9-7fe4-58c9-87b0-df0a1ae074a6
DOI: 10.1101/2023.06.14.544860

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