Article

Functional Characterization of Lipid Regulatory Effects of Three Genes Using Knockout Mouse Models

2021-07-02

Abstract excerpt

Integrative analysis that combines genome-wide association data with expression quantitative trait analysis and network representation may illuminate causal relationships between genes and diseases. To identify causal lipid genes, we utilized genotype, gene expression, protein-protein interaction networks, and phenotype data from 5,257 Framingham Heart Study participants and performed Mendelian randomization to in...

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Literature Corpus work: aaa851da-4fdd-5deb-b46a-9397a6c47011
DOI: 10.1101/2021.07.01.21259304

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