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Article

Exploring the causal effect between lipid-modifying drugs and idiopathic pulmonary fibrosis: a drug-target Mendelian randomization study.

Lipids in health and disease - 1 Aug 2024

Cai Gexiang, Liu Jingjing, Cai Mengsi, Shao Lianyou

Abstract excerpt

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a respiratory disorder of obscure etiology and limited treatment options, possibly linked to dysregulation in lipid metabolism. While several observational studies suggest that lipid-lowering agents may decrease the risk of IPF, the evidence is inconsistent. The present Mendelian randomization (MR) study aims to determine the association between circulating lipid...

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Angiopoietin-Like Protein 3
Angiopoietin-like Proteins
Apolipoprotein C-III
ATP Binding Cassette Transporter, Subfamily G, Member 5
ATP Binding Cassette Transporter, Subfamily G, Member 8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hydroxymethylglutaryl CoA Reductases

Hypolipidemic Agents

Idiopathic Pulmonary Fibrosis

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Identifiers

PMID: 39090671
DOI: 10.1186/s12944-024-02218-6
PMCID: PMC11293199

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