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Article

Genetic Association of Lipid-Lowering Drug Target Genes with Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Study.

COPD - 1 Dec 2025

Luan Hao, Wang Tianhua, Wang Rui, Wang Yu, Liu Yu, Sheng Wenru, Guo Jiaqi, Ji Haotian, Liu Xiufeng, Xue Xiqing, Tseng Yiider

Abstract excerpt

The role of lipid-lowering drugs in chronic obstructive pulmonary disease (COPD) is controversial in clinical studies. This study aimed to explore the causal relationship between lipid-lowering drugs and COPD from a genetic perspective, and to evaluate the potential effects of this relationship. Four hundred and thirty-one lipid-related phenotypes and two COPD datasets were obtained from Genome-Wide Association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 40522254
DOI: 10.1080/15412555.2025.2513601

Genes

HMGCR
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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