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Article

ZNF542P is a pseudogene associated with LDL response to simvastatin treatment

14 Aug 2018

Abstract excerpt

Statins are the most commonly prescribed cardiovascular disease drug, but their inter-individual efficacy varies considerably. Genetic factors uncovered to date have only explained a small proportion of variation in low-density lipoprotein cholesterol (LDLC) lowering. To identify novel markers and determinants of statin response, we used whole transcriptome sequence data collected from simvastatin and control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30127457
DOI: 10.1038/s41598-018-30859-y

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