Article

Multi-class Modeling Identifies Shared Genetic Risk for Late-onset Epilepsy and Alzheimer’s Disease

2024-02-06

Abstract excerpt

<h4>Background</h4> Previous studies have established a strong link between late-onset epilepsy (LOE) and Alzheimer’s disease (AD). However, their shared genetic risk beyond the APOE gene remains unclear. Our study sought to examine the shared genetic factors of AD and LOE, interpret the biological pathways involved, and evaluate how AD onset may be mediated by LOE and shared genetic risks. <h4>Methods</h4> We def...

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Literature Corpus work: 4907f4c6-17db-54b7-a866-36f06b9beee9
DOI: 10.1101/2024.02.05.24302353

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