Article

The Genetic Architecture of Alzheimer’s Disease Risk: A Genomic Structural Equation Modelling Study

2021-03-02

Abstract excerpt

<h4>Background</h4> Targeting modifiable risk factors may have a role in the prevention of Alzheimer’s disease. However, the mechanisms by which these risk factors influence Alzheimer’s risk remain incompletely understood. Genomic structural equation modelling can reveal patterns of shared genetic architecture that provide insight into the pathophysiology of complex traits. <h4>Methods</h4> We identified genome-wi...

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Literature Corpus work: 396ffaec-3728-54e6-83dd-d106ba2975d7
DOI: 10.1101/2021.02.23.21252211

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