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Article

Familial Alzheimer's Disease and Recessive Modifiers.

Molecular neurobiology - 1 Feb 2020

Vélez Jorge I, Lopera Francisco, Silva Claudia T, Villegas Andrés, Espinosa Lady G, Vidal Oscar M, Mastronardi Claudio A, Arcos-Burgos Mauricio

Abstract excerpt

Alzheimer's disease (AD) is progressive brain disorder that affects ~ 50 million people worldwide and has no current effective treatment. AD age of onset (ADAOO) has shown to be critical for the identification of genes that modify the appearance of AD signs and symptoms in a specific population. We clinically characterized and whole-exome genotyped 71 individuals with AD from the Paisa genetic isolate,...

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Identifiers

PMID: 31664702
DOI: 10.1007/s12035-019-01798-0
PMCID: PMC7031188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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