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Ligand-Displaying <i>E. coli</i> Cells and Minicells for Programmable Delivery of Toxic Payloads via Type IV Secretion Systems

2023-08-12

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial type IV secretion systems (T4SSs) are highly versatile macromolecular translocators and offer great potential for deployment as delivery systems for therapeutic intervention. One major T4SS subfamily, the conjugation machines, are well-adapted for delivery of DNA cargoes of interest to other bacteria or eukaryotic cells, but generally exhibit modest transfer frequencies and lack specif...

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Literature Corpus work
47a28aba-b1a6-5e5a-a9ff-287ac8556b5c
DOI
10.1101/2023.08.11.553016
Open publication

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Ligand-Displaying <i>E. coli</i> Cells and Minicells for Programmable Delivery of Toxic Payloads via Type IV Secretion SystemsDOI 10.1101/2023.08.11.553016
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