Article

pGGTOX: a versatile plasmid platform for recombination-based genome editing across <i>Enterobacteriaceae</i>

2025-11-11

Abstract excerpt

Precise genome editing in Enterobacteriaceae is essential for studying gene function, pathogenesis, and antimicrobial resistance, yet many current systems face host-specific and efficiency limitations. We developed pGGTOX, a modular plasmid platform that enables efficient homologous recombination–mediated genome editing across diverse Enterobacteriaceae , including Escherichia coli , Klebsiella pneumoniae , S...

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Literature Corpus work: b6cf69d2-81e0-511b-a267-4e46b41a18d9
DOI: 10.1101/2025.11.11.687829

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