Article

Coupling metabolic enhancement to plasmid spread enables programmable antimicrobial control

2026-02-25

Abstract excerpt

The rise of multidrug-resistant pathogens underscores the need for precise antimicrobial strategies that extend beyond conventional antibiotics. Conjugation-based approaches offer a powerful yet underexploited means of delivering targeted genetic interventions directly within microbial communities. In this work, we combined selective killing modules with rationally optimized conjugative vectors to target antibioti...

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Literature Corpus work: 425e95a4-6631-5bbc-a83f-e8338ec5f578
DOI: 10.64898/2026.02.25.707879

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