Article

Metal complexes and conjugation: Harnessing the power of cobalt complexes to curtail plasmid transfer

2023-11-27

Abstract excerpt

<h4>Background</h4> Antimicrobial resistance genes (ARG), such as extended spectrum β-lactamase (ESBL) and carbapenemase genes, are commonly carried on plasmids. Plasmids can transmit between bacteria, disseminate globally, and cause clinically important resistance. Therefore, targeting plasmids could reduce ARG prevalence, and restore the efficacy of existing antibiotics. Here, we assessed the effect of four pre...

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Literature Corpus work: b1030890-b508-5fd7-af86-26917a30961f
DOI: 10.1101/2023.11.24.568573

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