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Factors affecting CRISPR-Cas defense against antibiotic resistance plasmids harbored by <i>Enterococcus faecalis</i> laboratory model strains and clinical isolates

2025-03-11

Abstract excerpt

<h4>ABSTRACT</h4> Enterococcus faecalis is a Gram-positive bacterium and opportunistic pathogen that acquires resistance to a wide range of antibiotics by horizontal gene transfer (HGT). The rapid increase of multidrug-resistant (MDR) bacteria including MDR E. faecalis necessitates the development of alternative therapies and a deeper understanding of the factors that impact HGT. CRISPR-Cas systems provide seque...

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Literature Corpus work
8e536c22-3417-523b-a70a-0ab7d25a4229
DOI
10.1101/2025.03.10.642232
Open publication

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Factors affecting CRISPR-Cas defense against antibiotic resistance plasmids harbored by <i>Enterococcus faecalis</i> laboratory model strains and clinical isolatesDOI 10.1101/2025.03.10.642232
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