Article

Apoptosis-Induced Chromosomal Rearrangements as a Driver of Genomic Instability in Cancer （Preprint)

2025-09-19

Abstract excerpt

This article systematically synthesizes published evidence to propose a new conceptual model of apoptosis-induced chromosomal rearrangements as a driver of genomic instability in cancer. Nasopharyngeal carcinoma (NPC) is characterized by recurrent chromosomal aberrations, yet the origins of these structural mutations remain poorly understood. Emerging evidence supports a model in which oxidative stress and inflamm...

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Literature Corpus work: 4783edbb-a9b2-5445-98e4-29d9c7d0333e
DOI: 10.22541/au.175829744.43205511/v1

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