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Article

DNA Oncogenic Virus‐Induced Oxidative Stress, Genomic Damage, and Aberrant Epigenetic Alterations

1 Jan 2017

Abstract excerpt

Approximately 20% of human cancers is attributable to DNA oncogenic viruses such as human papillomavirus (HPV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). Unrepaired DNA damage is the most common and overlapping feature of these DNA oncogenic viruses and a source of genomic instability and tumour development. Sustained DNA damage results from unceasing production of reactive oxygen species and...

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PMID: 28740569
DOI: 10.1155/2017/3179421

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