Article

Chromosome breaks in breast cancers occur near herpes tumor virus sequences and explain why the cancer comes back

2021-11-10

Abstract excerpt

Breast cancer has a relentless tendency to come back after treatment. Analyses of public data from about 2100 breast cancers produce a model that explains this recurrence and implicates variants of Epstein-Barr viruses (EBV or Human Herpes Virus 4). These viruses cause chromosome breaks. Broken chromosome pieces rejoin abnormally, sometimes including two centromeres. Two centromeres on the same chromosome interfer...

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Literature Corpus work: 815860df-1f0b-5412-81ba-77850d8b03b0
DOI: 10.1101/2021.11.08.467751

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