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Article

Microhomology‐mediated repair machinery and its relationship with HPV‐mediated oncogenesis

1 May 2024

Abstract excerpt

Human Papillomaviruses (HPV) are a diverse family of non-enveloped dsDNA viruses that infect the skin and mucosal epithelia. Persistent HPV infections can lead to cancer frequently involving integration of the virus into the host genome, leading to sustained oncogene expression and loss of capsid and genome maintenance proteins. Microhomology-mediated double-strand break repair, a DNA double-stranded breaks...

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PMID: 38757834
DOI: 10.1002/jmv.29674

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