Article

Chemiluminescent probes allow for the rapid identification of colibactin-producing bacteria

2026-01-02

Abstract excerpt

<h4>ABSTRACT</h4> The pks (or clb ) gene cluster, which produces the genotoxic natural product colibactin, is encoded by human gut Enterobacteriaceae , including many commensal strains of E. coli . Colibactin crosslinks DNA and is implicated in colorectal cancer development, highlighting the importance of identifying colibactin-producing gut bacteria within biological samples. In this study, we develop phenox...

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Literature Corpus work: 475cf18a-cfec-5785-907d-50cf247315ec
DOI: 10.64898/2026.01.02.697419

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