Article

The gut bacterial natural product colibactin triggers induction of latent viruses in diverse bacteria

2021-05-24

Abstract excerpt

Colibactin is a chemically unstable small molecule genotoxin produced by multiple different bacteria, including members of the human gut microbiome. 1,2 While the biological activity of colibactin has been extensively investigated in mammalian systems, 3 little is known about its effects on other microorganisms. Here, we discover that colibactin targets bacteria carrying prophages, inducing lytic development via...

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Identifiers and source

Literature Corpus work: 95b8386c-7fa9-5687-b875-9578eadf6ea8
DOI: 10.1101/2021.05.24.445430

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