Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of pks+ Escherichia coli (E. coli) to Colon Carcinogenesis

30 May 2024

Abstract excerpt

Colorectal cancer (CRC) stands as a significant global health concern, ranking second in mortality and third in frequency among cancers worldwide. While only a small fraction of CRC cases can be attributed to inherited genetic mutations, the majority arise sporadically due to somatic mutations. Emerging evidence reveals gut microbiota dysbiosis to be a contributing factor, wherein polyketide synthase-positive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridium difficile and Clostridium perfringens research
Share to Gut microbiota and health
Share to Probiotics and Fermented Foods

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38930493
DOI: 10.3390/microorganisms12061111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of pks+ Escherichia coli (E. coli) to Colon CarcinogenesisPMID 38930493Read ↗

Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survivalSemantic proximity Read ↗

Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli.Semantic proximity Read ↗

Enrichment of colibactin-associated mutational signatures in unexplained colorectal polyposis patientsSemantic proximity Read ↗

The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors.Semantic proximity Read ↗

Contribution of pks+ E. coli mutations to colorectal carcinogenesis.Semantic proximity Read ↗

Intestinal bacteria and colorectal cancer: etiology and treatmentSemantic proximity Read ↗

A bacterial mutational footprint in colorectal cancer genomes.Semantic proximity Read ↗

Enrichment of colibactin-associated mutational signatures in unexplained colorectal polyposis patients.Semantic proximity Read ↗

Mechanistic dissection unmasks colibactin as a prevalent mutagenic driver of cancer.Semantic proximity Read ↗

Microbiome-Genome Crosstalk in Colorectal Cancer: Colibactin Signatures and Fusobacterium nucleatum in Epidemiology, Driver Selection, and Translation.Semantic proximity Read ↗

Gut microbiota and their derivatives in the progression of colorectal cancer: Mechanisms of action, genome and epigenome contributionsSemantic proximity Read ↗

Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavageSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.