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Genetic dissection of hippocampal sclerosis of ageing using magnetic resonance imaging surrogates

2025-03-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> Hippocampal sclerosis of aging (HS-aging) is frequently present in individuals over 85 who die with dementia. Recent studies suggest that some loci associated with Alzheimer’s disease (AD) may be more related to HS-aging. We aimed to find AD-associated SNPs potentially related to HS-aging. <h4>METHODS</h4> We assessed the relation of the AD polygenic risk score (AD-PRS) with...

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Literature Corpus work
471f6972-a652-5868-b0dd-0d93077fd368
DOI
10.1101/2025.03.10.25323307
Open publication

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Genetic dissection of hippocampal sclerosis of ageing using magnetic resonance imaging surrogatesDOI 10.1101/2025.03.10.25323307
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