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Article

Hippocampal Sclerosis of Aging, a Common Alzheimer's Disease 'Mimic': Risk Genotypes are Associated with Brain Atrophy Outside the Temporal Lobe.

Journal of Alzheimer's disease : JAD - 1 Jan 2016

Nho Kwangsik, Saykin Andrew J, Nelson Peter T

Abstract excerpt

Hippocampal sclerosis of aging (HS-Aging) is a common brain disease in older adults with a clinical course that is similar to Alzheimer's disease. Four single-nucleotide polymorphisms (SNPs) have previously shown association with HS-Aging. The present study investigated structural brain changes associated with these SNPs using surface-based analysis. Participants from the Alzheimer's Disease Neuroimaging...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27003218
DOI: 10.3233/JAD-160077
PMCID: PMC4978172

Genes

ABCC9
GRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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