Article

Effects of dibenzazepine compounds on human Nav1.2 channels and neuronal network activity: A systematic comparison

2024-09-23

Abstract excerpt

<h4>Background: </h4> and Purpose: Voltage-gated Na+ channels are critical therapeutic targets of anti-seizure medications. The structurally related compounds carbamazepine (CBZ), oxcarbazepine (OXC), eslicarbazepine acetate (ESL), and S-licacarbazepine (S-Lic) of the dibenzazepine family are generally presumed to exert similar effects; however, a comparative analysis under identical conditions is lacking. Here, w...

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Literature Corpus work: 456f709b-ce30-5e25-8b98-5d14eab42cd5
DOI: 10.22541/au.172708657.76144438/v1

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