Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulators of voltage-dependent calcium channels for the treatment of nervous system diseases.

Recent patents on CNS drug discovery - 1 Jun 2009

Takahashi Eiki, Niimi Kimie

Abstract excerpt

Voltage-dependent Ca(2+) channels (VDCCs) play important roles in physiological functions and pathological processes of the nervous system. Given that the precise regulation of Ca(2+) signaling is important for neuronal processes such as action potential generation, transmitter release, and synaptic plasticity, alterations in Ca(2+) current through VDCCs affect the functions of neurons and circuits. Central...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium Channel Blockers
Share to Calcium Channels
Share to Calcium Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Molecular

Share to Mutation

Share to Nervous System Diseases

Source

Identifiers

PMID: 19519559
DOI: 10.2174/157488909788453022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulators of voltage-dependent calcium channels for the treatment of nervous system diseases.PMID 19519559Read ↗

Application, Development History, and Current Status of T-Type Calcium Channel Inhibitors in Pain TreatmentSemantic proximity Read ↗

Ion channel pharmacology.Semantic proximity Read ↗

Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?Semantic proximity Read ↗

Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease.Semantic proximity Read ↗

Development of phenotypic assays for identifying novel blockers of L-type calcium channels in neurons.Semantic proximity Read ↗

Ca2+ channels and epilepsy.Semantic proximity Read ↗

Medicinal chemistry of neuronal voltage-gated sodium channel blockers.Semantic proximity Read ↗

Voltage-gated Sodium Channels and Blockers: An Overview and Where Will They Go?Semantic proximity Read ↗

KV Channel-Interacting Proteins in Neurological and Cardiovascular System: An Updated ReviewSemantic proximity Read ↗

Therapeutic Potential of Heterocyclic Compounds Targeting Mitochondrial Calcium Homeostasis and Signaling in Alzheimer’s Disease and Parkinson’s DiseaseSemantic proximity Read ↗

Ion Channels in Neurological Disorders.Semantic proximity Read ↗

L-type calcium channels and psychiatric disorders: A brief review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.