Article
Variable prediction accuracy of polygenic scores within an ancestry group
2019-05-07
Abstract excerpt
Fields as diverse as human genetics and sociology are increasingly using polygenic scores based on genome-wide association studies (GWAS) for phenotypic prediction. However, recent work has shown that polygenic scores have limited portability across groups of different genetic ancestries, restricting the contexts in which they can be used reliably and potentially creating serious inequities in future clinical appl...
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Identifiers and source
- Literature Corpus work
- 44656390-c64c-524d-a4a1-f08ebc30412a
- DOI
- 10.1101/629949