Article
Analysis of Polygenic Score Usage and Performance in Diverse Human Populations
2018-08-22
Abstract excerpt
Studies examining relationships between genotypic and phenotypic variation have historically been carried out on people of European ancestry. Efforts are underway to address this limitation, but until they succeed, the legacy of a Euro-centric bias will continue to hinder research, including the use of polygenic scores, which are individual-level metrics of genetic risk. Ongoing debate surrounds the generalizabili...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- a40435e6-3cd6-5f07-87f8-99848730088b
- DOI
- 10.1101/398396