Article

Decoding Phospho-Regulation and Flanking Regions in Autophagy-Associated Short Linear Motifs: A Case Study of Optineurin-LC3B Interaction

2023-09-30

Abstract excerpt

Short Linear Motifs (SLiMs) play a pivotal role in mediating interactions between intrinsically disordered proteins and their binding partners. SLiMs exhibit sequence degeneracy and undergo regulation through post-translational modifications, including phosphorylation. The flanking regions surrounding the core motifs also exert a crucial role in shaping the modes of interaction. In this study, we aimed to integrat...

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Literature Corpus work: 44425052-5f83-56f8-919b-b3d899f16e80
DOI: 10.1101/2023.09.30.560296

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