Article

The conformational and mutational landscape of the ubiquitin-like marker for the autophagosome formation in cancer

2019-05-10

Abstract excerpt

Autophagy is a cellular process to recycle damaged cellular components and its modulation can be exploited for disease treatments. A key autophagy player is a ubiquitin-like protein, LC3B. Compelling evidence attests the role of autophagy and LC3B in different cancer types. Many LC3B structures have been solved, but a comprehensive study, including dynamics, has not been yet undertaken. To address this knowledge g...

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Literature Corpus work: 08cebffb-af27-5b04-985a-9131de39fa1c
DOI: 10.1101/635284

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