Article
Why budding yeast overrides the DNA damage checkpoint
2025-08-02
Abstract excerpt
Checkpoints arrest biological processes and enhance chances for error correction. In many species ranging from budding yeast to human, checkpoints are eventually overridden despite persistent dam-age. Whether checkpoint override serves a biological function remains unclear. Here, we investigate this question in the context of the DNA damage checkpoint (DDC) in budding yeast. To demonstrate that DDC override increa...
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Identifiers and source
- Literature Corpus work
- 427a37ee-93d6-558c-8af6-26196968863d
- DOI
- 10.1101/2025.07.30.667764