Article
The Chromosome Transmission Fidelity Assay for Measuring Chromosome Loss in Yeast.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Duffy Supipi, Hieter Philip
Abstract excerpt
The budding yeast Saccharomyces cerevisiae has served as an excellent model system for studying highly conserved biological pathways including pathways involved in genome transmission and maintenance. The Chromosome Transmission Fidelity (CTF) colony color assay was developed to assess chromosome instability (CIN) in yeast, by monitoring the loss or gain during cell division of an artificial chromosome fragment...
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