Article

INSERT-seq enables high resolution mapping of genomically integrated DNA using nanopore sequencing

2022-05-25

Abstract excerpt

Comprehensive characterization of genome engineering with viral vectors, transposons, CRISPR/Cas mediated DNA integration and other DNA editors remains relevant for their development and safe use in human gene therapy. Currently, described methods for measuring DNA integration in edited cells rely on short read based technologies. Due to the repetitive nature of the human genome, short read based methods can poten...

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Literature Corpus work: 4238fe21-0e89-5123-b753-74ebc70dd2da
DOI: 10.1101/2022.05.25.493391

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