Article

Cas9 targeted enrichment of mobile elements using nanopore sequencing

2021-02-10

Abstract excerpt

Mobile element insertions (MEIs) are highly repetitive genomic sequences that contribute to inter- and intra-individual genetic variation and can lead to genetic disorders. Targeted and whole-genome approaches using short-read sequencing have been developed to identify reference and non-reference MEIs; however, the read length hampers detection of these elements in complex genomic regions. Here, we pair Cas9 targe...

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Literature Corpus work: 633c716d-4c79-505c-960b-4389871374d1
DOI: 10.1101/2021.02.10.430605

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