Article
Comprehensive identification of transposable element insertions using multiple sequencing technologies.
Nature communications - 22 Jun 2021
Chu Chong, Borges-Monroy Rebeca, Viswanadham Vinayak V, Lee Soohyun, Li Heng, Lee Eunjung Alice, Park Peter J
Abstract excerpt
Transposable elements (TEs) help shape the structure and function of the human genome. When inserted into some locations, TEs may disrupt gene regulation and cause diseases. Here, we present xTea (x-Transposable element analyzer), a tool for identifying TE insertions in whole-genome sequencing data. Whereas existing methods are mostly designed for short-read data, xTea can be applied to both short-read and...
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