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Article

Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jul 2012

Warner-Schmidt Jennifer L, Schmidt Eric F, Marshall John J, Rubin Amanda J, Arango-Lievano Margarita, Kaplitt Michael G, Ibañez-Tallon Ines, Heintz Nathaniel, Greengard Paul

Abstract excerpt

A large number of studies have demonstrated that the nucleus accumbens (NAC) is a critical site in the neuronal circuits controlling reward responses, motivation, and mood, but the neuronal cell type(s) underlying these processes are not yet known. Identification of the neuronal cell types that regulate depression-like states will guide us in understanding the biological basis of mood and its regulation by...

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Identifiers

PMID: 22733786
DOI: 10.1073/pnas.1209293109
PMCID: PMC3396525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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