Article

NAc-DBS corrects depression-like behaviors in CUMS mouse model via disinhibition of DA neurons in the VTA

2021-12-02

Abstract excerpt

Major depressive disorder (MDD) is characterized by diverse debilitating symptoms that include loss of motivation and anhedonia. If multiple medications, psychotherapy, and electroconvulsive therapy fail in some patients with MDD, their condition is then termed treatment – resistant depression (TRD). MDD can be associated with abnormalities in the reward–system–dopaminergic mesolimbic pathway, in which the nucleus...

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Literature Corpus work: 3cdee863-26fe-5708-bcbe-b82f20b626ef
DOI: 10.1101/2021.12.01.470503

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