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G1/S Boundary Activates Interferon and Inflammatory Response Genes

2023-08-26

Abstract excerpt

Interferons (IFNs) have various roles in antiviral immunity, including curbing the immune system to prevent tissue damage and stimulating adaptive immunity. Due to its protective and destructive properties, IFN expression is tightly regulated. In contrast to its tight regulatory control, IFN expression is highly heterogeneous across many cell types upon pathogenic stimulus. The basis for this heterogenous IFN expr...

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Identifiers and source

Literature Corpus work
41b87596-1e8d-5fdf-b927-c275aa2cbbb1
DOI
10.1101/2023.08.24.554683
Open publication

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