Article

West Nile virus-inclusive single-cell RNA sequencing reveals heterogeneity in the type I interferon response within single cells

2018-10-04

Abstract excerpt

<h4>ABSTRACT</h4> West Nile virus (WNV) is a neurotropic mosquito-borne flavivirus of global importance. Neuroinvasive WNV infection results in encephalitis and can lead to prolonged neurological impairment or death. Type I interferon (IFN-I) is crucial for promoting antiviral defenses through the induction of antiviral effectors, which function to restrict viral replication and spread. However, our understanding...

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Literature Corpus work: 47008dcd-7d07-5cf4-8314-bfeeb5dd3028
DOI: 10.1101/434852

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