Article

HCMV exploits STING signaling and counteracts IFN and ISG induction to facilitate dendritic cell infection

2022-01-13

Abstract excerpt

<title>Abstract</title> <p>Human cytomegalovirus (HCMV) is a widespread obligatory human pathogen causing life-threatening disease in immunocompromised hosts. Myeloid cells such as monocyte-derived dendritic cells (moDCs) are targets of HCMV. Here, we performed single-cell RNA sequencing, which revealed infection of most moDCs upon <italic>in vitro</italic> HCMV exposure, whereas only a fraction of them initiated...

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Literature Corpus work: 2ad04635-79e2-53e0-9862-9e51939ab21c
DOI: 10.21203/rs.3.rs-953016/v1

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