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Over-expression Screen of Interferon-Stimulated Genes Identifies RARRES3 as a Restrictor of <i>Toxoplasma gondii</i> Infection

2021-09-05

Abstract excerpt

Toxoplasma gondii is an important human pathogen infecting an estimated 1 in 3 people worldwide. The cytokine interferon gamma (IFNγ) is induced during infection and is critical for restricting T. gondii growth in human cells. Growth restriction is presumed to be due to the induction interferon stimulated genes (ISGs) that are upregulated to protect the host from infection. Although there are hundreds of ISGs ind...

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Literature Corpus work
ffc158d2-52db-5f3f-9e3e-cad8db80eb18
DOI
10.1101/2021.09.04.458998
Open publication

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Over-expression Screen of Interferon-Stimulated Genes Identifies RARRES3 as a Restrictor of <i>Toxoplasma gondii</i> InfectionDOI 10.1101/2021.09.04.458998
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