Article

Nongenic cancer-risk SNPs affect oncogenes, tumor suppressor genes, and immune function

2018-12-27

Abstract excerpt

Genome-wide associations studies (GWASes) have identified many germline genetic variants that are associated with an increased risk of developing cancer. However, how these single nucleotide polymorphisms (SNPs) alter biological function in a way that increases cancer risk is still largely unknown. We used a systems biology approach to analyze the regulatory role and functional associations of cancer-risk SNPs in...

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Literature Corpus work: 418f78d8-ac6d-53b9-844f-139392077170
DOI: 10.1101/507236

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