Article
Bipartite Community Structure of eQTLs.
PLoS computational biology - 1 Sept 2016
Platig John, Castaldi Peter J, DeMeo Dawn, Quackenbush John
Abstract excerpt
Genome Wide Association Studies (GWAS) and expression quantitative trait locus (eQTL) analyses have identified genetic associations with a wide range of human phenotypes. However, many of these variants have weak effects and understanding their combined effect remains a challenge. One hypothesis is that multiple SNPs interact in complex networks to influence functional processes that ultimately lead to complex...
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