Article

Connectivity of variants in eQTL networks dictates reproducibility and functionality

2019-01-09

Abstract excerpt

Network analyses are a natural approach for identifying genetic variants and genes that work together to drive disease phenotypes. The relationship between SNPs and genes, captured in expression quantitative trait locus (eQTL) analysis, can be represented as a network with edges connecting SNPs and genes. Existing network methods treat such edges as fixed and known when they are most often thresholded estimates fr...

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Literature Corpus work: 8cff37a9-7c06-5656-9a32-1ee18882516e
DOI: 10.1101/515551

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