A network-based approach to eQTL interpretation and SNP functional characterization

Abstract excerpt

<h4>Summary</h4> Expression quantitative trait locus (eQTL) analysis associates genotype with gene expression, but most eQTL studies only include cis -acting variants and generally examine a single tissue. We used data from 13 tissues obtained by the Genotype-Tissue Expression (GTEx) project v6.0 and, in each tissue, identified both cis - and trans -eQTLs. For each tissue, we represented significant associatio...

Topics

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• Gene Expression
• Gene Expression Regulation
• Gene Regulatory Networks
• Genetic Variation
• Genome-Wide Association Study
• Organ Specificity
• Quantitative Trait Loci
• Transcriptome

Identifiers and source

Literature Corpus work

79e88080-15ea-5168-9967-b25e64456f82

DOI

10.1101/086587