Mistranslating tRNA variants have anticodon- and sex-specific impacts on <i>Drosophila melanogaster</i>

Abstract excerpt

<h4>ABSTRACT</h4> Transfer RNAs (tRNAs) are vital in determining the specificity of translation. Mutations in tRNA genes can result in the misincorporation of amino acids into nascent polypeptides in a process known as mistranslation. Since mistranslation has different impacts, depending on the type of amino acid substitution, our goal here was to compare the impact of different mistranslating tRNA Ser variants...

Topics

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• Mutation
• Phosphoproteins
• Protein Biosynthesis
• Proteome
• Proteomics
• RNA, Transfer
• Saccharomyces cerevisiae
• Saccharomyces cerevisiae Proteins

Identifiers and source

Literature Corpus work

084715c4-9fea-5d89-893f-f687a1745dba

DOI

10.1101/2024.06.11.598535