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Functional and Molecular Characterization of PD1+ Tumor-Infiltrating Lymphocytes From Lung Cancer Patients

2021-01-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> The majority of infiltrating T-cells (TILs) in lung cancer are contained in the memory compartment and overexpress PD1 and have been associated with dysfunction. Antibody-mediated cancer immunotherapy targets inhibitory surface molecules, such as PD1, PD-L1, and CTLA-4, aiming to re-invigorate dysfunctional T cells.<bold>Methods</bold> Using fluorescence-activate...

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Literature Corpus work
40be5d32-5e2f-5fc7-9688-468026cd95ed
DOI
10.21203/rs.3.rs-152467/v1
Open publication

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Functional and Molecular Characterization of PD1+&nbsp;Tumor-Infiltrating Lymphocytes From Lung Cancer PatientsDOI 10.21203/rs.3.rs-152467/v1
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