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Contribution of resident and circulating precursors to tumor-infiltrating CD8 <sup>+</sup> T cell populations in non-small cell lung cancer patients

2020-08-15

Abstract excerpt

Tumor-infiltrating lymphocytes (TILs) in general, and CD8 + TILs in particular, represent a favorable prognostic factor in non-small cell lung cancer (NSCLC). The tissue origin, regenerative capacities, and differentiation pathways of TIL subpopulations, however, remain poorly understood. Using a combination of single cell RNA and T cell receptor (TCR) sequencing, we investigate the functional organization of TIL...

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Literature Corpus work
4bbd0b02-c23e-56a1-8e7d-b521d1d311dc
DOI
10.1101/2020.08.14.249789
Open publication

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Contribution of resident and circulating precursors to tumor-infiltrating CD8 <sup>+</sup> T cell populations in non-small cell lung cancer patientsDOI 10.1101/2020.08.14.249789
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