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Article

The Presence of CD11c+ B Cells with Potent Effector Memory Phenotype in Lung Adenocarcinoma Correlates with Overall Patient Survival.

Cancer immunology research - 4 May 2026

Sambanthamoorthy Sharmila, Ren Yan, Galvez Tatiana K, King Benjamin, Liu Scot D, Kidd Brian A, Law Debbie A, Baumgarth Nicole

Abstract excerpt

Tumor-infiltrating B lymphocytes (TIL-B) are increasingly recognized as favorable prognostic markers in multiple cancer types, and the mechanisms underlying this are being actively investigated. In this study of TIL-Bs, we identified CD79A as a reliable quantifier of B lymphocytes and evaluated transcriptomic data for 15 distinct tumors using 8,720 samples of treatment naïve patients from The Cancer Genome Atlas...

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Topics

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Share to Adenocarcinoma of Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD11c Antigen

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Source

Open in PubMed Open full text

Identifiers

PMID: 41686183
DOI: 10.1158/2326-6066.CIR-25-0635
PMCID: PMC12988592

Genes

CD79A
CD4
CD40
CD8A
IL21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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