Article

Cell type specific profiling of alternative translation identifies novel protein isoforms in the mouse brain

2018-05-16

Abstract excerpt

Translation canonically begins at a single AUG and terminates at the stop codon, generating one protein species per transcript. However, some transcripts may use alternative initiation sites or sustain translation past their stop codon, generating multiple protein isoforms. Through other mechanisms such as alternative splicing, both neurons and glia exhibit remarkable transcriptional diversity, and these other for...

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Literature Corpus work: 401072b7-1bc5-5f4a-b239-928c06b4f6ea
DOI: 10.1101/324236

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