Article
Beyond proteome diversity: alternative splicing as a regulator of neuronal transcript dynamics.
Current opinion in neurobiology - 1 Aug 2017
Mauger Oriane, Scheiffele Peter
Abstract excerpt
Brain development and function are governed by tightly controlled gene expression programs. Transcriptional repertoires in neurons are highly specific to developmental stage, neuronal cell type and can undergo rapid changes upon neuronal stimulation. Dedicated molecular mechanisms are required to achieve such fine-tuned regulation. In addition to transcriptional programs, post-transcriptional processes and...
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